FertDish: microfluidic sperm selection-in-a-dish for intracytoplasmic sperm injection
نویسندگان
چکیده
The FertDish features a clinically applicable sperm processing format, and enables high recovery of motile with DNA quality.
منابع مشابه
Intracytoplasmic Sperm Injection
Intracytoplasmic Sperm Injection (ICSI) is an assisted reproductive technique [4] (ART) initially developed by Dr. Gianpiero D. Palermo [5] in 1993 to treat male infertility [6]. It is most commonly used in conjunction with in vitro [7] fertilization [8] (IVF) or a less commonly used technique called zygote intrafallopian transfer [9] (ZIFT). In natural fertilization [8], the sperm [10] must pe...
متن کاملIntracytoplasmic sperm injection (ICSI)
IVF has become a well-established treatment for certain types of infertility, including long-standing infertility due to tubal disease, endometriosis, unexplained infertility or infertility involving a male factor. Soon it became clear that certain couples with severe male-factor infertility could not be helped by conventional IVF. Extremely low sperm counts, impaired motility and/or abnormal m...
متن کاملIndications for intracytoplasmic sperm injection.
Intracytoplasmic sperm injection (ICSI) is the latest of several microfertilization techniques that have been utilized predominantly to overcome severe male subfertility, giving fertilization and term pregnancy rates similar to conventional in-vitro fertilization (IVF) (but for other indications). Even though available data on children born after ICSI are very encouraging, the procedure must st...
متن کاملIntracytoplasmic sperm injection: a novel selection method for sperm with normal frequency of chromosomal aneuploidies.
OBJECTIVE To test a newly invented intracytoplasmic sperm injection (ICSI) sperm selection method based on sperm hyaluronic acid (HA) binding. DESIGN Comparison of chromosomal disomy and diploidy frequencies in sperm arising from semen and in HA-bound sperm. SETTING Academic andrology laboratory. PATIENT(S) Men presenting for semen analysis. INTERVENTION(S) Washed sperm fractions of 32 ...
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ژورنال
عنوان ژورنال: Lab on a Chip
سال: 2021
ISSN: ['1473-0197', '1473-0189']
DOI: https://doi.org/10.1039/d0lc00874e